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Creatine Non-Responders: Why Some People Don't Benefit

May 22, 2024 . By Bea Llagas

If you frequent the wellness aisles at your local supermarket, chances are you’ve seen bottles of creatine on the shelves. We’ve all seen the hype about creatine—it helps you build muscle and improve your performance. It’s popular among bodybuilders, athletes, and even casual gym-goers.


But what if you’re putting in the work and not feeling the benefits everyone talks about? Relax, this doesn’t automatically mean you’re a creatine “non-responder.” Just because you’re not seeing immediate results doesn’t mean it’s not working. It can take a few weeks for your body to stock up and unleash its potential fully. Plus, a couple of things can influence how you experience creatine.

 

Why You Might Not Be Feeling the Creatine Magic

A recent review of creatine research took a fresh look at the concept of “non-responders.” They re-examined early studies on creatine's effectiveness. Interestingly, the review found that many of these original studies involved participants from countries where red meat consumption (a natural source of creatine) is lower than in the United States. This raises the possibility that baseline creatine levels due to diet might have influenced the results.


Here are other reasons why you’re not getting the full benefits of creatine:

 

Dietary Factors

Creatine is naturally found in red meat, poultry, and fish. So, if your diet is already heavy on these protein sources, your body might already have higher baseline creatine levels. Supplementation might not create a dramatic difference, but it can still be helpful!

 

Muscle Fiber Composition

Your muscles are made of different fiber types. Type II fibers are the explosive powerhouses that benefit most from creatine. If you have more Type I fibers (a.k.a. the endurance all-stars), you might not see the same creatine hype.

 

Absorption Differences

Your body might need practice absorbing creatine. There can be slight variations in how efficiently your body takes it up, which can affect how much your muscles actually use. This could affect how much gets utilized and the overall effect.

 

Underlying Health Conditions

Certain medical conditions or medications may interfere with the body’s ability to absorb or utilize creatine effectively, leading to a reduced response to supplementation.

 

How To Maximize Your Creatine Experience

 

    • Consistency: Don’t skip out on your creatine. Take the recommended daily amount consistently for optimal benefits.
    • Hydration: Dehydration can mess with creatine absorption. Make sure you’re chugging plenty of water throughout the day.
    • Talk to Your Nutritionist Coach: They can help you assess your individual needs and see if there are any other factors at play.
    • Get More Bang for Your (Creatine) Buck: Stick to creatine monohydrate and make sure you look for a brand that’s particular with the ingredients they use (think natural, vegan, and sugar-free!).

 

Our Takeaway

The good news? Research shows most women benefit from creatine supplementation. It can be a powerful tool to boost your performance and help you crush your goals. Don’t get discouraged by a slow start. Give your body time, use it correctly, and consider talking to a nutritionist for personalized advice.


Bonus Tip: Beyond the gym, creatine might also be a teammate for your brain. Early research suggests creatine supplementation could offer benefits for cognitive function, especially for vegetarians who might have lower natural creatine stores. Studies are ongoing, but it’s an interesting area to keep an eye on, especially if you’re looking for ways to stay sharp alongside your fitness goals.

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